SCHEMBL9515430

SCHEMBL9515430

CC(C)(C(=O)O[Si](C)(C)C)C(=O)O[Si](C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10923610 0.82 ELANE (0.34)
SCHEMBL31042742 0.78
SCHEMBL31300447 0.78
SCHEMBL10584849 0.78
SCHEMBL19582475 0.78
SCHEMBL31272574 0.78
SCHEMBL7612398 0.76
SCHEMBL10012260 0.76 DGAT1 (0.30) DGAT1
SCHEMBL1086612 0.74 ALDH1A1 (0.33)
SCHEMBL4758776 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4824981-A REACTING MALONATES WITH TRIALKYLSILANES, ALKALI METAL AND DIALKYLMALONIC ACID; PURITY DOW CORNING CORPORATION (US) 1989-04-25 US claimed
EP-0298363-B1 A process to produce silyl ketene acetals DOW CORNING (US) 1993-12-01 EP disclosed
US-4824981-A REACTING MALONATES WITH TRIALKYLSILANES, ALKALI METAL AND DIALKYLMALONIC ACID; PURITY DOW CORNING CORPORATION (US) 1989-04-25 US disclosed
EP-0298363-A2 A process to produce silyl ketene acetals DOW CORNING CORPORATION (US) 1989-01-11 EP disclosed