Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517204 | 0.85 | P4HTM (0.43) | P4HTMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9515946 | 0.81 | P4HTM (0.40) | P4HTMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9515522 | 0.80 | LMNA (0.37) | P4HTMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9518012 | 0.80 | MEN1 (0.37) | P4HTMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9516127 | 0.79 | MMP1 (0.37) | P4HTMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9519311 | 0.78 | P4HTM (0.36) | P4HTMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9517212 | 0.78 | P4HTM (0.43) | P4HTMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9515891 | 0.78 | EGFR (0.41) | P4HTMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9515444 | 0.77 | P4HTM (0.41) | P4HTMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9515545 | 0.77 | HDAC6 (0.36) | P4HTMNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |