Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16233212 | 0.91 | POLB (0.64) | ALDH1A1CYP1A2POLBGAAMEN1 | |
| SCHEMBL16233236 | 0.88 | MEN1 (0.61) | ALDH1A1CYP1A2POLBGAAMEN1 | |
| SCHEMBL31178415 | 0.88 | KMT2A (0.83) | ALDH1A1POLBGAAMEN1KMT2A | |
| SCHEMBL9512949 | 0.88 | KMT2A (0.83) | ALDH1A1POLBGAAMEN1KMT2A | |
| SCHEMBL11847732 | 0.88 | KDM4E (0.76) | ALDH1A1CYP1A2POLBMEN1KMT2A | |
| SCHEMBL25242104 | 0.84 | KMT2A (0.77) | ALDH1A1POLBGAAMEN1KMT2A | |
| SCHEMBL31178346 | 0.84 | KMT2A (0.77) | ALDH1A1POLBGAAMEN1KMT2A | |
| Ethylbenzene SCHEMBL9588439 | 0.83 | SLC29A1 (0.60) | ALDH1A1CYP1A2POLBMEN1KMT2A | |
| Ethylbenzene SCHEMBL9588148 | 0.82 | SLC29A1 (0.59) | ALDH1A1CYP1A2POLBMEN1KMT2A | |
| SCHEMBL25284686 | 0.81 | DRD2 (0.75) | ALDH1A1POLBGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0250361-B1 | Disubstituted piperazines | CIBA GEIGY AG (CH) | 1993-12-08 | — | — | EP | disclosed |