Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519522 | 0.91 | P4HTM (0.46) | P4HTMEGFRBCL2L1MCL1TP53 | |
| SCHEMBL9516113 | 0.88 | P4HTM (0.44) | P4HTMEGFRBCL2L1MCL1 | |
| SCHEMBL9519377 | 0.87 | P4HTM (0.45) | P4HTMEGFRBCL2L1MCL1USP2 | |
| SCHEMBL9566780 | 0.86 | KMT2A (0.45) | P4HTMTP53MAPT | |
| SCHEMBL9518074 | 0.82 | P4HTM (0.39) | P4HTMEGFRBCL2L1MCL1PTGS2 | |
| SCHEMBL9517920 | 0.80 | P4HTM (0.51) | P4HTMEGFRBCL2L1MCL1GFER | |
| SCHEMBL9517044 | 0.78 | P4HTM (0.47) | P4HTMEGFRBCL2L1MCL1 | |
| SCHEMBL8869937 | 0.78 | P4HTM (0.52) | P4HTMEGFRBCL2L1MCL1 | |
| SCHEMBL9515597 | 0.76 | P4HTM (0.48) | P4HTMEGFRBCL2L1MCL1PTGS2 | |
| SCHEMBL9566768 | 0.76 | P4HTM (0.46) | P4HTMTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |