Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517920 | 0.90 | P4HTM (0.51) | P4HTMNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL9519522 | 0.87 | P4HTM (0.46) | P4HTMNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL9515597 | 0.86 | P4HTM (0.48) | P4HTMNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL9515686 | 0.86 | P4HTM (0.62) | P4HTMEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL9517172 | 0.83 | BCL2L1 (0.50) | P4HTMBCL2L1MCL1SCN9A | |
| SCHEMBL9566814 | 0.83 | P4HTM (0.47) | P4HTMNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9517241 | 0.83 | P4HTM (0.61) | P4HTMEGFRBCL2L1MCL1 | |
| SCHEMBL9516113 | 0.79 | P4HTM (0.44) | P4HTMNPC1RAB9ASMN1; SMN2EGFR | |
| SCHEMBL9515580 | 0.78 | P4HTM (0.43) | P4HTMEGFRBCL2L1MCL1 | |
| SCHEMBL9519274 | 0.77 | SCN3A (0.51) | P4HTMBCL2L1MCL1EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |