Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 7/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515580 | 0.88 | P4HTM (0.43) | P4HTMEGFRBCL2L1MCL1 | |
| SCHEMBL9519377 | 0.88 | P4HTM (0.45) | P4HTMEGFRBCL2L1MCL1 | |
| SCHEMBL9566765 | 0.85 | P4HTM (0.49) | P4HTMSCN9ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8869926 | 0.83 | P4HTM (0.47) | P4HTMEGFRBCL2L1MCL1SCN9A | |
| SCHEMBL9515461 | 0.83 | P4HTM (0.62) | P4HTMEGFRSMN1; SMN2 | |
| SCHEMBL9518074 | 0.83 | P4HTM (0.39) | P4HTMEGFRBCL2L1MCL1SCN9A | |
| SCHEMBL9517186 | 0.82 | BCL2L1 (0.54) | P4HTMEGFRBCL2L1MCL1 | |
| SCHEMBL7862810 | 0.81 | P4HTM (0.39) | P4HTMEGFRBCL2L1MCL1SCN9A | |
| SCHEMBL9517920 | 0.81 | P4HTM (0.51) | P4HTMEGFRBCL2L1MCL1SCN9A | |
| SCHEMBL9515532 | 0.80 | P4HTM (0.61) | P4HTMEGFRBCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |