Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.45 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517038 | 0.89 | P4HTM (0.43) | P4HTMAGTR2BCL2L1MCL1AGTR1 | |
| SCHEMBL9515484 | 0.89 | P4HTM (0.43) | P4HTMAGTR2AGTR1 | |
| SCHEMBL9518048 | 0.88 | P4HTM (0.43) | P4HTMBCL2L1MCL1TDP1 | |
| SCHEMBL9519091 | 0.88 | P4HTM (0.42) | P4HTMAGTR2BCL2L1MCL1AGTR1 | |
| SCHEMBL9515762 | 0.88 | P4HTM (0.49) | P4HTMAGTR2AGTR1HDAC1HDAC6 | |
| SCHEMBL9516257 | 0.83 | P4HTM (0.64) | P4HTMEDNRAMCL1 | |
| SCHEMBL9142936 | 0.82 | P4HTM (0.55) | P4HTMEDNRA | |
| SCHEMBL9018103 | 0.80 | P4HTM (0.45) | P4HTMEDNRAAGTR2BCL2L1MCL1 | |
| SCHEMBL9516931 | 0.80 | FABP4 (0.51) | P4HTM | |
| SCHEMBL9516246 | 0.80 | P4HTM (0.41) | P4HTMBCL2L1MCL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |