Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | FES | P07332 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | MARK3 | P27448 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515551 | 0.92 | PTGER4 (0.42) | P4HTMPTGER4DCLK1DYRK3ROCK2 | |
| SCHEMBL9518048 | 0.92 | P4HTM (0.43) | P4HTMGAAPTGER4DCLK1DYRK3 | |
| SCHEMBL9515456 | 0.90 | P4HTM (0.44) | P4HTMGAAPTGER4DCLK1DYRK3 | |
| SCHEMBL9516999 | 0.89 | P4HTM (0.41) | P4HTMGAAPTGER4DCLK1DYRK3 | |
| SCHEMBL9515484 | 0.88 | P4HTM (0.43) | P4HTMSCN9AKCNH2SCN5A | |
| SCHEMBL9515461 | 0.80 | P4HTM (0.62) | P4HTMGAAPTGER4EGFRFLT4 | |
| SCHEMBL9515592 | 0.80 | P4HTM (0.45) | P4HTMTDP1MCL1BCL2L1 | |
| SCHEMBL9515532 | 0.79 | P4HTM (0.61) | P4HTMEGFRKAT6AMCL1BCL2L1 | |
| SCHEMBL9518028 | 0.78 | FABP4 (0.48) | P4HTMKMT2A | |
| SCHEMBL9517038 | 0.76 | P4HTM (0.43) | P4HTMMCL1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |