Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 5/20 | 0.36 |
| ▸ | NOS3 | P29474 | 3/20 | 0.36 |
| ▸ | NOS1 | P29475 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27412837 | 1.00 | NOS2 (0.36) | NOS2NOS3NOS1SLC6A3SLC6A4 | |
| SCHEMBL9519053 | 0.86 | NOS2 (0.34) | NOS2NOS3NOS1SLC6A3SLC6A4 | |
| SCHEMBL9580434 | 0.77 | NOS2 (0.34) | NOS2NOS3NOS1SLC6A3SLC6A4 | |
| SCHEMBL9580450 | 0.77 | NOS2 (0.34) | NOS2NOS3NOS1SLC6A3SLC6A4 | |
| SCHEMBL9516906 | 0.77 | NOS2 (0.34) | NOS2NOS3NOS1SLC6A3SLC6A4 | |
| SCHEMBL9516910 | 0.77 | NOS2 (0.34) | NOS2NOS3NOS1SLC6A3SLC6A4 | |
| SCHEMBL9515635 | 0.75 | NPSR1 (0.36) | SLC6A3SLC6A4SLC6A2NPSR1 | |
| SCHEMBL9580474 | 0.75 | HDAC3 (0.36) | NOS2NOS3NOS1 | |
| SCHEMBL9517705 | 0.75 | HDAC3 (0.36) | NOS2NOS3NOS1 | |
| SCHEMBL9517708 | 0.75 | HDAC3 (0.36) | NOS2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369762-B1 | Pesticides | ROUSSEL UCLAF (FR) | 1993-12-29 | — | — | EP | claimed |
| US-5202356-A | Insecticides, miticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-13 | — | — | US | claimed |
| EP-0369762-A1 | Pesticides | ROUSSEL-UCLAF (FR) | 1990-05-23 | — | — | EP | claimed |
| US-5202356-A | Insecticides, miticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-13 | — | — | US | disclosed |