Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 10/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.47 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | DRD1 | P21728 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515724 | 1.00 | BCHE (0.48) | BCHEGRM5GRM7GRM3CHRM2 | |
| SCHEMBL9531549 | 0.81 | POLB (0.44) | BCHECHRM2SLC6A2SLC6A3KCNH2 | |
| SCHEMBL9531554 | 0.81 | POLB (0.44) | BCHECHRM2SLC6A2SLC6A3KCNH2 | |
| SCHEMBL9353058 | 0.79 | CHRM2 (0.55) | BCHEGRM5GRM7GRM3CHRM2 | |
| SCHEMBL9533720 | 0.78 | CHRM2 (0.59) | BCHECHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9353307 | 0.77 | SLC6A3 (0.52) | BCHEGRM5GRM7GRM3CHRM2 | |
| SCHEMBL9353353 | 0.77 | CHRM2 (0.57) | BCHEGRM5GRM7GRM3CHRM2 | |
| SCHEMBL9353069 | 0.77 | BCHE (0.56) | BCHEGRM5GRM7GRM3CHRM2 | |
| SCHEMBL9674245 | 0.77 | BCHE (0.59) | BCHECHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL10435985 | 0.77 | BCHE (0.59) | BCHEGRM5GRM7GRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5017442-A | — | — | None | — | — | JP | disclosed |
| JP-H0517442-A | PIPERIDINE DERIVATIVE | HOKURIKU SEIYAKU CO LTD | 1993-01-26 | — | — | JP | disclosed |