Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | CTSE | P14091 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515771 | 1.00 | REN (0.49) | RENCTSDCTSECTSSCTSK | |
| SCHEMBL9518196 | 0.90 | REN (0.51) | RENCTSDCTSECTSSCTSK | |
| SCHEMBL9518203 | 0.90 | REN (0.51) | RENCTSDCTSECTSSCTSK | |
| SCHEMBL10774812 | 0.89 | REN (0.50) | RENCTSSCTSKCTSL | |
| SCHEMBL10774805 | 0.89 | REN (0.50) | RENCTSSCTSKCTSL | |
| SCHEMBL10774796 | 0.89 | REN (0.50) | RENCTSSCTSKCTSL | |
| SCHEMBL9514521 | 0.88 | REN (0.51) | RENCTSDCTSECTSSCTSK | |
| SCHEMBL9514515 | 0.88 | REN (0.51) | RENCTSDCTSECTSSCTSK | |
| SCHEMBL9832026 | 0.86 | REN (0.55) | RENCTSDCTSECTSL | |
| SCHEMBL9832827 | 0.85 | REN (0.54) | RENCTSDCTSECTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266950-B1 | Nor-statine and nor-cyclostatine polypeptides | PFIZER (US) | 1993-12-29 | — | — | EP | disclosed |
| US-5034376-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1991-07-23 | — | — | US | disclosed |
| US-4935405-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1990-06-19 | — | — | US | disclosed |
| US-4814342-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1989-03-21 | — | — | US | disclosed |
| EP-0266950-A2 | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1988-05-11 | — | — | EP | disclosed |