Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517883 | 0.90 | P4HTM (0.47) | P4HTMMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL9519579 | 0.90 | P4HTM (0.47) | P4HTMMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL9517123 | 0.88 | P4HTM (0.45) | P4HTMMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL9517336 | 0.86 | P4HTM (0.44) | P4HTMMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL9517081 | 0.84 | FABP4 (0.51) | P4HTMMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL9517968 | 0.82 | P4HTM (0.69) | P4HTMMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9518028 | 0.78 | FABP4 (0.48) | P4HTMMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL9517023 | 0.77 | P4HTM (0.62) | P4HTMMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9516931 | 0.76 | FABP4 (0.51) | P4HTMALDH1A1L3MBTL1LMNAHTT | |
| SCHEMBL9518008 | 0.76 | P4HTM (0.54) | P4HTMKMT2AALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |