Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515565 | 0.91 | BCL2L1 (0.53) | P4HTMEGFRBCL2L1MCL1SMN1; SMN2 | |
| SCHEMBL9518006 | 0.89 | P4HTM (0.67) | P4HTMEGFRTDP1KMT2A | |
| SCHEMBL9519133 | 0.89 | BCL2L1 (0.51) | P4HTMEGFRBCL2L1MCL1SMN1; SMN2 | |
| SCHEMBL9516980 | 0.88 | BCL2L1 (0.50) | P4HTMEGFRBCL2L1MCL1SMN1; SMN2 | |
| SCHEMBL9519606 | 0.88 | BCL2L1 (0.50) | P4HTMEGFRBCL2L1MCL1SMN1; SMN2 | |
| SCHEMBL9516188 | 0.88 | BCL2L1 (0.50) | P4HTMEGFRBCL2L1MCL1SMN1; SMN2 | |
| SCHEMBL9515471 | 0.86 | P4HTM (0.52) | P4HTMEGFRBCL2L1MCL1ALDH1A1 | |
| SCHEMBL9517238 | 0.86 | P4HTM (0.55) | P4HTMEGFRBCL2L1MCL1 | |
| SCHEMBL9517152 | 0.86 | BCL2L1 (0.48) | P4HTMEGFRBCL2L1MCL1SMN1; SMN2 | |
| SCHEMBL9519310 | 0.85 | EGFR (0.51) | P4HTMEGFRBCL2L1MCL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |