Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1917616 | 0.84 | CYP2D6 (0.36) | ALDH1A1SOAT1MAPTCYP2D6KMT2A | |
| SCHEMBL9515797 | 0.79 | CHRNB2 (0.34) | ALDH1A1MAPTKMT2APOLBL3MBTL1 | |
| SCHEMBL11203639 | 0.75 | ALDH1A1 (0.46) | ALDH1A1SOAT1MAPTLMNACYP2D6 | |
| SCHEMBL9830385 | 0.73 | MAPT (0.49) | ALDH1A1MAPTLMNAKMT2APOLB | |
| SCHEMBL11198763 | 0.69 | ALDH1A1 (0.39) | ALDH1A1SOAT1MAPTLMNACYP2D6 | |
| SCHEMBL10361297 | 0.69 | CYP2D6 (0.51) | ALDH1A1MAPTLMNACYP2D6KMT2A | |
| SCHEMBL2130385 | 0.68 | ALDH1A1 (0.46) | ALDH1A1SOAT1MAPTLMNACYP2D6 | |
| SCHEMBL8708999 | 0.67 | CHRM4 (0.47) | ALDH1A1SOAT1CYP2D6POLBL3MBTL1 | |
| SCHEMBL8709003 | 0.67 | CHRM4 (0.47) | ALDH1A1SOAT1CYP2D6POLBL3MBTL1 | |
| SCHEMBL5741816 | 0.67 | ALDH1A1 (0.36) | ALDH1A1SOAT1MAPTCYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538692-A1 | Use of partly known substituted pyrrolidine derivatives as pharmaceuticals, new compounds and process for their preparation | BAYER AG (DE) | 1993-04-28 | — | — | EP | disclosed |