Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FABP7 | O15540 | 3/20 | 0.40 |
| ▸ | FABP3 | P05413 | 3/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9323234 | 0.79 | PTGS1 (0.50) | HSD17B10KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL1855181 | 0.75 | ATM (0.48) | HSD17B10KMT2AALDH1A1MEN1RAB9A | |
| SCHEMBL10595010 | 0.74 | HSD17B10 (0.54) | HSD17B10KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL6362824 | 0.73 | TACR1 (0.53) | HSD17B10KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL5438064 | 0.73 | TACR1 (0.53) | HSD17B10KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL3290432 | 0.73 | HSD17B10 (0.56) | HSD17B10KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL29519974 | 0.72 | CTSL (0.57) | KMT2AALDH1A1GAAMEN1RAB9A | |
| SCHEMBL1855157 | 0.72 | CYP1A2 (0.53) | HSD17B10ALDH1A1PTGS1PPARGPPARA | |
| SCHEMBL28048746 | 0.71 | HSD17B10 (0.57) | HSD17B10KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL8664311 | 0.71 | HSD17B10 (0.57) | HSD17B10KMT2AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511228-A4 | ESTERS OF 2-ARYLMETHYL-1-NAPHTHOL DERIVATIVES AS 5-LIPOXYGENASE INHIBITORS | — | 1993-04-21 | — | — | EP | disclosed |