Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 14/20 | 0.64 |
| ▸ | RXRB | P28702 | 11/20 | 0.64 |
| ▸ | RXRG | P48443 | 8/20 | 0.64 |
| ▸ | RARB | P10826 | 7/20 | 0.64 |
| ▸ | RARG | P13631 | 7/20 | 0.64 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.53 |
| ▸ | RARA | P10276 | 5/20 | 0.53 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674121 | 0.81 | RXRA (0.69) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL15554765 | 0.80 | RXRA (0.67) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8674842 | 0.80 | RXRA (0.68) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7723487 | 0.79 | RXRA (1.00) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL5078263 | 0.79 | RXRA (0.65) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8676840 | 0.77 | RXRB (0.71) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL9208986 | 0.76 | RXRA (0.78) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8839242 | 0.76 | RXRA (0.69) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL28949691 | 0.74 | RXRA (0.58) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7789857 | 0.74 | NR1H4 (0.51) | RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386452-B1 | DIPHENYL HETEROALKYL DERIVATIVES, THEIR PREPARATION AND MEDICINAL AND COSMETIC PREPARATIONS PREPARED THEREFROM | BASF Aktiengesellschaft (DE) | 1993-09-22 | — | — | EP | disclosed |