Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 15/20 | 0.69 |
| ▸ | RXRB | P28702 | 11/20 | 0.69 |
| ▸ | RXRG | P48443 | 8/20 | 0.69 |
| ▸ | RARB | P10826 | 8/20 | 0.69 |
| ▸ | RARG | P13631 | 8/20 | 0.69 |
| ▸ | RARA | P10276 | 5/20 | 0.59 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15554765 | 0.88 | RXRA (0.67) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7723487 | 0.82 | RXRA (1.00) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8839140 | 0.82 | RXRA (0.65) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL9515841 | 0.81 | RXRA (0.64) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL9208986 | 0.79 | RXRA (0.78) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8839257 | 0.79 | RXRA (0.69) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL9526508 | 0.79 | RXRA (0.65) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL14286039 | 0.77 | CYP26B1 (0.70) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL9318594 | 0.77 | RXRA (0.70) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8460878 | 0.77 | RXRA (0.70) | RXRARXRBRXRGRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739374-A | Processes of preparing diphenylheteroalkyl derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1998-04-14 | — | — | US | disclosed |
| US-5656619-A | Diphenylheteroalkyl derivatives, the preparation thereof and drugs and cosmetics prepared therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1997-08-12 | — | — | US | disclosed |
| US-5527945-A | Diphenylheteroalkyl derivatives, the preparation thereof and drugs and cosmetics prepared therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-18 | — | — | US | disclosed |
| US-5248823-A | Diphenylheteroalkyl derivatives, the preparation thereof and drugs and cosmetics prepared therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-28 | — | — | US | disclosed |
| EP-0386452-B1 | DIPHENYL HETEROALKYL DERIVATIVES, THEIR PREPARATION AND MEDICINAL AND COSMETIC PREPARATIONS PREPARED THEREFROM | BASF Aktiengesellschaft (DE) | 1993-09-22 | — | — | EP | disclosed |
| US-5225601-A | Sulfur containing compounds for skin disorders | BASF AKTIENGESELLSCHAFT (DE) | 1993-07-06 | — | — | US | disclosed |
| EP-0386452-A1 | Diphenyl heteroalkyl derivatives, their preparation and medicinal and cosmetic preparations prepared therefrom | BASF Aktiengesellschaft (DE) | 1990-09-12 | — | — | EP | disclosed |