SCHEMBL537849

SCHEMBL537849

C(=Cc1nc2ccccc2s1)c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.69
MEN1 O00255 5/20 0.69
KMT2A Q03164 5/20 0.69
RAB9A P51151 5/20 0.69
SMN1; SMN2 Q16637 3/20 0.69
APP P05067 1/20 0.69
INSR P06213 1/20 0.69
NCOA1 Q15788 1/20 0.69
NPC1 O15118 3/20 0.64
CYP1A2 P05177 1/20 0.64
CYP3A4 P08684 1/20 0.64
CYP2D6 P10635 1/20 0.64
CYP2C19 P33261 1/20 0.64
NPSR1 Q6W5P4 1/20 0.64
TDP1 Q9NUW8 1/20 0.59
KDM4E B2RXH2 2/20 0.58
GAA P10253 2/20 0.58
ALDH1A1 P00352 1/20 0.58
POLB P06746 1/20 0.58
HTT P42858 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL537848 1.00 MAPT (0.69) MAPTMEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL31063726 1.00 MAPT (0.69) MAPTMEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL319385 0.94 MEN1 (0.77) MAPTMEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL319386 0.94 MEN1 (0.77) MAPTMEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL29559249 0.94 MEN1 (0.77) MAPTMEN1KMT2ARAB9ASMN1; SMN2
Dimethylamine SCHEMBL11573253 0.93 MAPT (0.67) MAPTMEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL11776645 0.89 MAPT (0.57) MAPTMEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL23111674 0.86 MAPT (0.67) MAPTMEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL2628251 0.86 MEN1 (0.67) MAPTMEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL6606615 0.86 MEN1 (0.67) MAPTMEN1KMT2ARAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118492850-A Preparation process of ferrochrome wire for electrode sealing 江苏鸿科金属科技有限公司 2024-08-16 CN claimed
CN-106518860-B A kind of hypochlorous acid scale fluorescence probe of the targetted mitochondria based on fluorescence resonance energy transfer mechanism and its application 山东大学 2019-03-26 CN claimed
CN-106831641-B Benzothiazole derivatives and preparation method thereof 浙江工业大学 2019-03-19 CN claimed
CN-106831641-A Benzothiazole derivatives and preparation method thereof 浙江工业大学 2017-06-13 CN claimed
CN-106518860-A Fluorescence resonance energy transfer (FRET) mechanism based ratio fluorescent probe for hypochlorous acid in targeting mitochondrion and application thereof 山东大学 2017-03-22 CN claimed
US-8815000-B1 Solid inks comprising liquid crystalline materials XEROX CORPORATION (US) 2014-08-26 US claimed
US-20140225956-A1 SOLID INKS COMPRISING LIQUID CRYSTALLINE MATERIALS XEROX CORPORATION (US) 2014-08-14 US claimed
CN-102762555-A Fluorescent cell markers BEATRIZ BEATRIZ ZAYAS 2012-10-31 CN claimed
EP-2414355-A2 FLUORESCENT CELLULAR MARKERS Zayas, Beatriz (US) 2012-02-08 EP claimed
WO-2010135751-A2 FLUORESCENT CELLULAR MARKERS BEATRIZ ZAYAS BEATRIZ (US) 2010-11-25 WO claimed
US-20100256378-A1 FLUORESCENT CELLULAR MARKERS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-10-07 US claimed
US-4063894-A CHROMOGEN, HYDROPEROXIDE, THIAZOLE SHIONOGI & CO., LTD. (JA) 1977-12-20 US claimed
JP-1172831-A None JP disclosed
JP-1161245-A None JP disclosed
WO-2026087600-A1 STYRYL BENZOTHIAZOLIUM SALTS AND ITS USES AGAINST PARASITIC INFECTIONS CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) 2026-04-30 WO disclosed
EP-4732907-A1 STYRYL BENZOTHIAZOLIUM SALTS AND ITS USES AGAINST PARASITIC INFECTIONS Consejo Superior de Investigaciones Científicas (CSIC) (ES) 2026-04-29 EP disclosed
EP-0041274-A1 Fluorescent composition having the ability to change wavelengths of light, shaped article of said composition as a light wavelength converting element, and device for converting optical energy to electrical energy using said element TEIJIN LIMITED (JP) 1981-12-09 EP disclosed
US-4063894-A CHROMOGEN, HYDROPEROXIDE, THIAZOLE SHIONOGI & CO., LTD. (JA) 1977-12-20 US disclosed
US-3994724-A SUBSTITUTED ANILINE PHOTOCONDUCTOR SCOTT PAPER COMPANY (US) 1976-11-30 US disclosed
US-3912697-A Light-sensitive polymers EASTMAN KODAK CO 1975-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256378-A1 FLUORESCENT CELLULAR MARKERS AIFM1, CASP3, BAX MAPT 3510/4885MEN1 2951/4885KMT2A 1656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.