Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | TTR | P02766 | 6/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1477136 | 0.86 | TSHR (0.61) | TSHRTTRPTPN1SRD5A2KDM4E | |
| SCHEMBL31214608 | 0.81 | TTR (0.65) | TSHRTTRSRD5A2KDM4EALDH1A1 | |
| SCHEMBL7840769 | 0.81 | MEN1 (0.52) | TSHRTTRGRIN2DGRIN2AGRIN2C | |
| SCHEMBL10081743 | 0.80 | GRIN2D (0.66) | TSHRTTRGRIN2DGRIN2AGRIN2C | |
| SCHEMBL7088722 | 0.79 | PTPN1 (0.64) | TSHRGRIN2DGRIN2AGRIN2CPTPN1 | |
| SCHEMBL29904704 | 0.78 | PTPN1 (0.59) | TSHRGRIN2DGRIN2AGRIN2CPTPN1 | |
| SCHEMBL31401727 | 0.78 | PTPN1 (0.59) | TSHRGRIN2DGRIN2AGRIN2CPTPN1 | |
| SCHEMBL1879909 | 0.78 | PTPN1 (0.59) | TSHRGRIN2DGRIN2AGRIN2CPTPN1 | |
| SCHEMBL1880299 | 0.77 | PTPN1 (0.58) | TSHRGRIN2DGRIN2AGRIN2CPTPN1 | |
| SCHEMBL8383171 | 0.77 | PLAU (0.50) | TSHRTTRGRIN2DGRIN2AGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042571-A | Fire-retardant polyamides from naphthalene dicarboxylic reactant and halogenated carboxylic reactant | TEIJIN LIMITED (JA) | 1977-08-16 | — | — | US | claimed |
| EP-0424860-B1 | Wholly aromatic polyamides, process for their preparation and products therefrom | HOECHST AG (DE) | 1993-12-01 | — | — | EP | disclosed |
| US-5097015-A | Fibers, filaments, films and sheets | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | disclosed |
| EP-0424860-A2 | Wholly aromatic polyamides, process for their preparation and products therefrom | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-02 | — | — | EP | disclosed |