Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28102737 | 0.93 | ALDH1A1 (0.48) | TSHRNAAAEPHX1ALDH1A1HCAR2 | |
| SCHEMBL11396719 | 0.88 | NAAA (0.50) | TSHRNAAAEPHX1ALDH1A1HCAR2 | |
| SCHEMBL28556796 | 0.88 | NAAA (0.53) | TSHRNAAAEPHX1ALDH1A1HCAR2 | |
| SCHEMBL28563002 | 0.88 | NAAA (0.53) | TSHRNAAAEPHX1ALDH1A1HCAR2 | |
| SCHEMBL1261012 | 0.86 | ALDH1A1 (0.52) | TSHRNAAAEPHX1ALDH1A1HCAR2 | |
| SCHEMBL7687964 | 0.86 | NAAA (0.55) | TSHRNAAAEPHX1ALDH1A1HCAR2 | |
| SCHEMBL7681798 | 0.86 | NAAA (0.55) | TSHRNAAAEPHX1ALDH1A1HCAR2 | |
| SCHEMBL28549732 | 0.86 | NAAA (0.50) | TSHRNAAAEPHX1ALDH1A1HCAR2 | |
| SCHEMBL7681788 | 0.86 | NAAA (0.55) | TSHRNAAAEPHX1ALDH1A1HCAR2 | |
| SCHEMBL7684054 | 0.86 | NAAA (0.55) | TSHRNAAAEPHX1ALDH1A1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372527-B1 | TOPICAL COMPOSITIONS CONTAINING DICLOFENAC | ALTERGON S.A. (CH) | 1993-05-12 | — | — | EP | disclosed |
| EP-0372527-A1 | Topical compositions containing diclofenac | ALTERGON S.A. (CH) | 1990-06-13 | — | — | EP | disclosed |