Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 12/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 11/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515728 | 0.93 | P4HTM (0.45) | MCL1BCL2L1P4HTMPTGS2PTGS1 | |
| SCHEMBL9519096 | 0.90 | BCL2L1 (0.53) | MCL1BCL2L1P4HTMPTGS2PTGS1 | |
| SCHEMBL9516981 | 0.90 | BCL2L1 (0.60) | MCL1BCL2L1MMP1MMP13P4HTM | |
| SCHEMBL9519730 | 0.88 | MCL1 (0.62) | MCL1BCL2L1MMP1MMP13P4HTM | |
| SCHEMBL9516995 | 0.88 | MCL1 (0.49) | MCL1BCL2L1MMP1MMP13P4HTM | |
| SCHEMBL9516252 | 0.87 | BCL2L1 (0.50) | MCL1BCL2L1MMP13P4HTMEGFR | |
| SCHEMBL9517006 | 0.84 | EGFR (0.50) | MCL1BCL2L1P4HTMPTGS2PTGS1 | |
| SCHEMBL9517198 | 0.83 | EGFR (0.62) | MCL1BCL2L1MMP1P4HTMPTGS2 | |
| SCHEMBL9517224 | 0.82 | BCL2L1 (0.49) | MCL1BCL2L1MMP1MMP13P4HTM | |
| SCHEMBL9515436 | 0.82 | BCL2L1 (0.56) | MCL1BCL2L1P4HTMPTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1079466-A | 4-or 5-(sulphur) acylimino-and (inferior sulphur) amidopyridine and pyridine-N-oxide thereof | HOECHST AG (DE) | 1993-12-15 | — | — | CN | disclosed |
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |