Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.47 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516252 | 0.90 | BCL2L1 (0.50) | BCL2L1MCL1P4HTMEGFRMAPK14 | |
| SCHEMBL9516981 | 0.88 | BCL2L1 (0.60) | BCL2L1MCL1P4HTMEGFRMMP1 | |
| SCHEMBL9515597 | 0.87 | P4HTM (0.48) | BCL2L1MCL1P4HTMEGFRPTGS2 | |
| SCHEMBL9519730 | 0.87 | MCL1 (0.62) | BCL2L1MCL1P4HTMEGFRMMP1 | |
| SCHEMBL9517198 | 0.86 | EGFR (0.62) | BCL2L1MCL1P4HTMEGFRMMP1 | |
| SCHEMBL9515436 | 0.83 | BCL2L1 (0.56) | BCL2L1MCL1P4HTMEGFRPTGS2 | |
| SCHEMBL9516149 | 0.82 | MCL1 (0.53) | BCL2L1MCL1P4HTMEGFRMMP1 | |
| SCHEMBL9518006 | 0.82 | P4HTM (0.67) | P4HTMEGFRMMP1MMP2MMP9 | |
| SCHEMBL9519377 | 0.81 | P4HTM (0.45) | BCL2L1MCL1P4HTMEGFRPTGS2 | |
| SCHEMBL9518008 | 0.81 | P4HTM (0.54) | BCL2L1MCL1P4HTMEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |