Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 8/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 8/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517224 | 0.90 | BCL2L1 (0.49) | BCL2L1MCL1MMP2MMP3MMP9 | |
| SCHEMBL9516149 | 0.87 | MCL1 (0.53) | BCL2L1MCL1MMP13P4HTMEGFR | |
| SCHEMBL9519730 | 0.86 | MCL1 (0.62) | BCL2L1MCL1MMP2MMP13MMP14 | |
| SCHEMBL8868123 | 0.85 | BCL2L1 (0.49) | BCL2L1MCL1MMP2MMP3MMP9 | |
| SCHEMBL9519096 | 0.83 | BCL2L1 (0.53) | BCL2L1MCL1P4HTMPGREGFR | |
| SCHEMBL9143139 | 0.83 | P4HTM (0.48) | BCL2L1MCL1MMP2MMP3MMP9 | |
| SCHEMBL9516981 | 0.83 | BCL2L1 (0.60) | BCL2L1MCL1MMP2MMP9MMP13 | |
| SCHEMBL7870464 | 0.83 | BCL2L1 (0.45) | BCL2L1MCL1MMP2MMP3MMP9 | |
| SCHEMBL9018320 | 0.83 | RAB9A (0.49) | BCL2L1MCL1MMP2MMP3MMP9 | |
| SCHEMBL8868192 | 0.82 | P4HTM (0.49) | BCL2L1MCL1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |