Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515565 | 0.89 | BCL2L1 (0.53) | P4HTMBCL2L1MCL1MMP1ADAMTS4 | |
| SCHEMBL9519133 | 0.87 | BCL2L1 (0.51) | P4HTMBCL2L1MCL1MMP1ADAMTS4 | |
| SCHEMBL9519606 | 0.86 | BCL2L1 (0.50) | P4HTMBCL2L1MCL1MMP1ADAMTS4 | |
| SCHEMBL9516980 | 0.86 | BCL2L1 (0.50) | P4HTMBCL2L1MCL1MMP1ADAMTS4 | |
| SCHEMBL9516188 | 0.86 | BCL2L1 (0.50) | P4HTMBCL2L1MCL1MMP1ADAMTS4 | |
| SCHEMBL9517920 | 0.85 | P4HTM (0.51) | P4HTMBCL2L1MCL1SMN1; SMN2HDAC3 | |
| SCHEMBL9517152 | 0.84 | BCL2L1 (0.48) | P4HTMBCL2L1MCL1MMP1ADAMTS4 | |
| SCHEMBL8870173 | 0.83 | P4HTM (0.62) | P4HTMBCL2L1MCL1MMP1ADAMTS4 | |
| SCHEMBL7874636 | 0.82 | P4HTM (0.52) | P4HTMBCL2L1MCL1MMP1ADAMTS4 | |
| SCHEMBL9515461 | 0.81 | P4HTM (0.62) | P4HTMMMP1MMP2MMP13SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |