Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515532 | 0.87 | P4HTM (0.61) | P4HTMEGFR | |
| SCHEMBL9515759 | 0.87 | P4HTM (0.58) | P4HTMEGFRTDP1MMP2HTT | |
| SCHEMBL9516185 | 0.87 | EGFR (0.57) | P4HTMEGFRMMP1FLT1FLT4 | |
| SCHEMBL9517186 | 0.87 | BCL2L1 (0.54) | P4HTMEGFRMMP1MMP2MMP9 | |
| SCHEMBL9515686 | 0.87 | P4HTM (0.62) | P4HTMGFERHSD17B10EGFRHDAC3 | |
| SCHEMBL9518006 | 0.86 | P4HTM (0.67) | P4HTMGFERHSD17B10EGFRHDAC3 | |
| SCHEMBL9517235 | 0.85 | BCL2L1 (0.52) | P4HTMEGFRFLT1FLT4KDR | |
| SCHEMBL9519132 | 0.84 | ALDH1A1 (0.47) | P4HTMHSD17B10EGFRCA1CA2 | |
| SCHEMBL9516113 | 0.83 | P4HTM (0.44) | P4HTMEGFRSMN1; SMN2 | |
| SCHEMBL9516250 | 0.83 | CA2 (0.46) | P4HTMEGFRTDP1CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |