Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519606 | 1.00 | BCL2L1 (0.50) | BCL2L1MCL1P4HTMADAMTS4MMP1 | |
| SCHEMBL9516188 | 1.00 | BCL2L1 (0.50) | BCL2L1MCL1P4HTMADAMTS4MMP1 | |
| SCHEMBL9519133 | 0.99 | BCL2L1 (0.51) | BCL2L1MCL1P4HTMADAMTS4MMP1 | |
| SCHEMBL9515565 | 0.97 | BCL2L1 (0.53) | BCL2L1MCL1P4HTMADAMTS4MMP1 | |
| SCHEMBL9517152 | 0.92 | BCL2L1 (0.48) | BCL2L1MCL1P4HTMADAMTS4MMP1 | |
| SCHEMBL9518008 | 0.88 | P4HTM (0.54) | BCL2L1MCL1P4HTMMAPTSMN1; SMN2 | |
| SCHEMBL9517947 | 0.86 | NPC1 (0.56) | BCL2L1MCL1TP53NPC1MAPT | |
| SCHEMBL9516161 | 0.86 | P4HTM (0.53) | BCL2L1MCL1P4HTMADAMTS4MMP1 | |
| SCHEMBL9517238 | 0.86 | P4HTM (0.55) | BCL2L1MCL1P4HTMEGFR | |
| SCHEMBL9519322 | 0.85 | CA2 (0.56) | P4HTMNPC1RXFP1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1079466-A | 4-or 5-(sulphur) acylimino-and (inferior sulphur) amidopyridine and pyridine-N-oxide thereof | HOECHST AG (DE) | 1993-12-15 | — | — | CN | disclosed |
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |