Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513630 | 0.79 | ALDH1A1 (0.42) | SMN1; SMN2HPGDEGFRLMNAMAPT | |
| SCHEMBL9513564 | 0.79 | PIK3CA (0.44) | MEN1KMT2ANPC1HPGDL3MBTL1 | |
| SCHEMBL1593360 | 0.79 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2EGFRERBB2LMNA | |
| SCHEMBL9515104 | 0.79 | CTBP2 (0.43) | MEN1KMT2ANPC1SMN1; SMN2HPGD | |
| SCHEMBL3485127 | 0.78 | CES1 (0.50) | MEN1KMT2AL3MBTL1LMNAHTT | |
| SCHEMBL17802296 | 0.77 | MEN1 (0.46) | TGM2MEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL9817167 | 0.75 | HTT (0.53) | NPC1SMN1; SMN2LMNAHTTMAPT | |
| SCHEMBL17599981 | 0.75 | ALDH1A1 (0.47) | MEN1KMT2ANPC1SMN1; SMN2HPGD | |
| SCHEMBL9513745 | 0.75 | TYR (0.44) | MEN1KMT2ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8858040 | 0.73 | MEN1 (0.41) | MEN1KMT2ANPC1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274379-B1 | PROCESS FOR PREPARING PYRIDINE-2,3-DICARBOXYLIC ACID COMPOUNDS | SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |
| US-4973695-A | FROM UNSATURATED ALDEHYDE OR KETONE WITH OXODIESTER | SUGAI CHEMICAL IND. CO., LTD. (JP) | 1990-11-27 | — | — | US | disclosed |
| EP-0274379-A2 | Process for preparing pyridine-2,3-dicarboxylic acid compounds | SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-07-13 | — | — | EP | disclosed |