Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515104 | 0.83 | CTBP2 (0.43) | ALDH1A1SMN1; SMN2LMNAHPGDCYP2C19 | |
| SCHEMBL12802223 | 0.81 | LPL (0.40) | ALDH1A1LPLLIPGPLK1EGFR | |
| SCHEMBL9513564 | 0.79 | PIK3CA (0.44) | ALDH1A1EGFRLMNAMAPTHPGD | |
| SCHEMBL1593360 | 0.79 | SMN1; SMN2 (0.47) | ALDH1A1EGFRSMN1; SMN2LMNA | |
| SCHEMBL9516170 | 0.79 | TGM2 (0.42) | EGFRSMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL17599981 | 0.79 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPTHPGDCYP2A6 | |
| SCHEMBL9817167 | 0.79 | HTT (0.53) | ALDH1A1SMN1; SMN2LMNAMAPTTP53 | |
| SCHEMBL9513745 | 0.79 | TYR (0.44) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL3485127 | 0.78 | CES1 (0.50) | ALDH1A1LMNAMAPTCYP2C9 | |
| SCHEMBL17802304 | 0.77 | ALDH1A1 (0.48) | ALDH1A1LPLLIPGPLK1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274379-B1 | PROCESS FOR PREPARING PYRIDINE-2,3-DICARBOXYLIC ACID COMPOUNDS | SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |
| US-4973695-A | FROM UNSATURATED ALDEHYDE OR KETONE WITH OXODIESTER | SUGAI CHEMICAL IND. CO., LTD. (JP) | 1990-11-27 | — | — | US | disclosed |
| EP-0274379-A2 | Process for preparing pyridine-2,3-dicarboxylic acid compounds | SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-07-13 | — | — | EP | disclosed |