SCHEMBL9516207

SCHEMBL9516207

O=C1OC(=O)C2C(Cl)CC=CC12

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
GMNN O75496 1/20 0.33
PPM1B O75688 1/20 0.33
LMNA P02545 1/20 0.33
PPP1CC P36873 1/20 0.33
TFPI2 P48307 1/20 0.33
RAB9A P51151 1/20 0.33
PPP5C P53041 1/20 0.33
PPP1CA P62136 1/20 0.33
PMP22 Q01453 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TP53 P04637 1/20 0.33
CYP2D6 P10635 1/20 0.33
NFKB1 P19838 1/20 0.33
THPO P40225 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15466 0.77 KDM4E (0.33) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL10343798 0.77 KDM4E (0.33) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL10813414 0.77 KDM4E (0.33) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL2297002 0.73 KDM4E (0.31) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL10432287 0.73 CYP3A4 (0.35) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL284839 0.73 MEN1 (0.35) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL15854380 0.71 FNTA (0.30)
SCHEMBL7202230 0.70
SCHEMBL10594909 0.69
SCHEMBL19681983 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0330219-B1 Preparation of substituted phthalic anhydride OCCIDENTAL CHEM CO (US) 1993-12-29 EP claimed
US-5003088-A Method for the preparation of halophthalic anhydrides OCCIDENTAL CHEMICAL CORPORATION (US) 1991-03-26 US claimed
US-4978760-A Preparation of halogen substituted phthalic anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1990-12-18 US claimed
EP-0338215-A2 Process for the preparation of halogen-substituted phthalic anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1989-10-25 EP claimed
EP-0334049-A2 Process for the preparation of halogen-substituted phthalic anhydrides OCCIDENTAL CHEMICAL CORPORATION (US) 1989-09-27 EP claimed
EP-0330219-A2 Preparation of substituted phthalic anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1989-08-30 EP claimed
JP-1249764-A None JP disclosed
CN-115521279-B Preparation method of 4-halophthalic anhydride and 4-halophthalic anhydride obtained by using same 中国石油化工股份有限公司 2024-03-26 CN disclosed
CN-115521279-A Preparation method of 4-halogenated phthalic anhydride and 4-halogenated phthalic anhydride obtained by using method 中国石油化工股份有限公司 2022-12-27 CN disclosed
US-5059697-A Preparation of halogenated phthalic anhydrides OCCIDENTAL CHEMICAL CORPORATION (US) 1991-10-22 US disclosed
JP-H01249764-A PREPARATION OF SUBSTITUTED PHTHALIC ANHYDRIDE OCCIDENTAL CHEM CORP 1989-10-05 JP disclosed
EP-0201719-A1 Process for preparing polycarboxylic acid NEW JAPAN CHEMICAL CO.,LTD. (JP) 1986-11-20 EP disclosed
US-4460783-A AMIDATION, CYCLIZATION, DEHYDRATION HITACHI, LTD. (JP) 1984-07-17 US disclosed
EP-0028419-A2 Imides and process for producing the same Hitachi, Ltd. (JP) 1981-05-13 EP disclosed