Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | FNTA | P49354 | 1/20 | 0.55 |
| ▸ | FNTB | P49356 | 1/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.54 |
| ▸ | RRM1 | P23921 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.52 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.51 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.51 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20503323 | 0.85 | FNTA (0.68) | MMP8FNTAFNTBDPP7RRM1 | |
| SCHEMBL10769018 | 0.81 | MMP8 (0.51) | MMP8FNTAFNTBDPP7RRM1 | |
| SCHEMBL28303860 | 0.80 | DPP7 (0.56) | MMP8FNTAFNTBDPP7RRM1 | |
| SCHEMBL6654724 | 0.80 | DPP7 (0.56) | MMP8FNTAFNTBDPP7RRM1 | |
| SCHEMBL8767020 | 0.79 | GNAI3 (0.60) | MMP8FNTAFNTBDPP7RRM1 | |
| SCHEMBL8766649 | 0.79 | GNAI3 (0.60) | MMP8FNTAFNTBDPP7RRM1 | |
| SCHEMBL8767404 | 0.79 | GNAI3 (0.60) | MMP8FNTAFNTBDPP7RRM1 | |
| Hydrochloric Acid SCHEMBL10805159 | 0.78 | USP2 (0.42) | MMP8FNTAFNTBDPP7RRM1 | |
| SCHEMBL13609211 | 0.77 | USP2 (0.68) | MMP8FNTAFNTBDPP7RRM1 | |
| SCHEMBL1489369 | 0.76 | FNTA (0.66) | MMP8FNTAFNTBDPP7RRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410726-B1 | S-SUBSTITUTED BETA-THIOACRYLAMIDES AND THEIR USE AS MICROBICIDES | ROHM AND HAAS COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5118681-A | Bactericides | ROHM AND HAAS COMPANY (US) | 1992-06-02 | — | — | US | disclosed |
| EP-0410726-A1 | S-substituted beta-thioacrylamides and their use as microbicides | ROHM AND HAAS COMPANY (US) | 1991-01-30 | — | — | EP | disclosed |