Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.59 |
| ▸ | CES2 | O00748 | 2/20 | 0.59 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938412 | 0.86 | CES2 (0.61) | CES1CES2PARP1HDAC1HDAC6 | |
| SCHEMBL1273634 | 0.86 | CES1 (0.65) | CES1CES2PARP1HDAC1HDAC6 | |
| SCHEMBL30166168 | 0.86 | CES1 (0.65) | CES1CES2PARP1HDAC1HDAC6 | |
| SCHEMBL28513115 | 0.81 | CES1 (0.59) | CES1CES2PARP1HDAC1HDAC6 | |
| SCHEMBL11848528 | 0.80 | CES2 (0.53) | CES1CES2PARP1HDAC1HDAC6 | |
| SCHEMBL4661246 | 0.78 | CES2 (0.61) | CES1CES2PARP1HDAC1HDAC6 | |
| SCHEMBL9861767 | 0.77 | CES1 (0.67) | CES1CES2PARP1MEN1KMT2A | |
| SCHEMBL3819330 | 0.76 | CES2 (0.57) | CES1CES2PARP1HDAC1HDAC6 | |
| SCHEMBL103051 | 0.75 | CES2 (0.68) | CES1CES2PARP1HDAC1HDAC6 | |
| SCHEMBL29604318 | 0.75 | CES2 (0.68) | CES1CES2PARP1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411252-B1 | Process for the preparation of fluorobenzoic acids | RIEDEL DE HAEN AG (DE) | 1993-11-03 | — | — | EP | disclosed |
| US-5093529-A | Process for the preparation of fluorinated benzoic acids | CASSELLA AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| EP-0411252-A1 | Process for the preparation of fluorobenzoic acids | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1991-02-06 | — | — | EP | disclosed |