SCHEMBL9516643

SCHEMBL9516643

CO[Si](C)(C)CCCN1CCCCC1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 8/20 0.48
CYP1A2 P05177 2/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
KCNH2 Q12809 1/20 0.37
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
HRH1 P35367 2/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP2D6 P10635 1/20 0.36
KMT2A Q03164 1/20 0.36
HRH4 Q9H3N8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20357829 0.86 CSNK2A2 (0.43) HRH3MAPTALDH1A1
SCHEMBL2852223 0.84 HRH3 (0.48) HRH3CYP1A2MAPK1SMN1; SMN2KCNH2
SCHEMBL611596 0.84 HRH3 (0.48) HRH3CYP1A2MAPK1SMN1; SMN2KCNH2
SCHEMBL8100830 0.82 HRH3 (0.46) HRH3CYP1A2MAPK1SMN1; SMN2KCNH2
SCHEMBL3482540 0.82 SMN1; SMN2 (0.48) HRH3CYP1A2MAPK1SMN1; SMN2KCNH2
SCHEMBL1995694 0.82 HRH3 (0.44) HRH3CYP1A2MAPK1SMN1; SMN2KCNH2
SCHEMBL1229250 0.82 HRH3 (0.50) HRH3CYP1A2MAPK1SMN1; SMN2KCNH2
SCHEMBL614666 0.82 HRH3 (0.50) HRH3CYP1A2MAPK1SMN1; SMN2KCNH2
SCHEMBL16714779 0.81 HRH3 (0.45) HRH3CYP1A2MAPK1SMN1; SMN2KCNH2
SCHEMBL4059390 0.81 CSNK2A2 (0.37) HRH3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0417755-B1 Packing for chromatography and its use for separating water soluble organic compounds DAISO CO LTD (JP) 1993-12-29 EP claimed
US-5103000-A PACKING FOR CHROMATOGRAPHY AND METHOD FOR SEPARATING WATER SOLUBLE ORGANIC COMPOUNDS USING THE SAME DAISO CO., LTD. (JP) 1992-04-07 US claimed
CN-104650357-B Composition and preparation method thereof comprising nitrogenous organic oxysilane compound 信越化学工业株式会社 2019-08-02 CN disclosed
US-9862812-B2 Composition containing nitrogen-containing organoxysilane compound and method for making the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-09 US disclosed
EP-2876111-B1 Composition containing nitrogen-containing organoxysilane compound and method for making the same SHINETSU CHEMICAL CO (JP) 2017-09-20 EP disclosed
EP-2876111-A1 Composition containing nitrogen-containing organoxysilane compound and method for making the same Shin-Etsu Chemical Co., Ltd. (JP) 2015-05-27 EP disclosed
CN-104650357-A Composition containing nitrogen-containing organoxysilane compound and method for making the same SHINETSU CHEMICAL CO 2015-05-27 CN disclosed
US-20150135996-A1 COMPOSITION CONTAINING NITROGEN-CONTAINING ORGANOXYSILANE COMPOUND AND METHOD FOR MAKING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-05-21 US disclosed
EP-0417755-B1 Packing for chromatography and its use for separating water soluble organic compounds DAISO CO LTD (JP) 1993-12-29 EP disclosed
US-5103000-A PACKING FOR CHROMATOGRAPHY AND METHOD FOR SEPARATING WATER SOLUBLE ORGANIC COMPOUNDS USING THE SAME DAISO CO., LTD. (JP) 1992-04-07 US disclosed
EP-0417755-A1 Packing for chromatography and its use for separating water soluble organic compounds DAISO CO., LTD. (JP) 1991-03-20 EP disclosed