Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10828662 | 0.79 | — | — | |
| SCHEMBL10689140 | 0.79 | LMNA (0.36) | — | |
| SCHEMBL11216997 | 0.79 | LMNA (0.36) | — | |
| SCHEMBL9238840 | 0.79 | LMNA (0.36) | — | |
| Hydrochloric Acid SCHEMBL9718743 | 0.78 | LMNA (0.35) | — | |
| SCHEMBL28217892 | 0.75 | ALDH1A1 (0.32) | — | |
| SCHEMBL11352695 | 0.73 | TDP1 (0.31) | — | |
| SCHEMBL7918011 | 0.71 | MEN1 (0.33) | — | |
| SCHEMBL7532816 | 0.70 | MAPK1 (0.38) | — | |
| SCHEMBL14839676 | 0.70 | MAPK1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002849-B1 | PROCESS FOR THE PREPARATION OF DI-(HALO)-VINYL COMPOUNDS AND DI-(HALO)-VINYL COMPOUNDS PRODUCED THEREBY | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1982-01-27 | — | — | EP | claimed |
| EP-0258815-B1 | DERIVATIVES OF 2,2-DIMETHYL-CYCLOPROPANECARBOXYLIC ACID | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1993-04-07 | — | — | EP | disclosed |
| US-4902697-A | Derivatives of 2,2-dimethyl-cyclopropanecarboxylic acid | MONTEDISON S.P.A. (IT) | 1990-02-20 | — | — | US | disclosed |
| EP-0258815-A2 | Derivatives of 2,2-dimethyl-cyclopropanecarboxylic acid | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1988-03-09 | — | — | EP | disclosed |