Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | PYGL | P06737 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11816723 | 0.86 | MEN1 (0.61) | SMN1; SMN2TSHRMAPTKMT2AMEN1 | |
| SCHEMBL7071167 | 0.84 | MAPT (0.47) | SMN1; SMN2TSHRMAPTKMT2AMEN1 | |
| SCHEMBL7071164 | 0.84 | MAPT (0.47) | SMN1; SMN2TSHRMAPTKMT2AMEN1 | |
| SCHEMBL6137229 | 0.82 | GLO1 (0.56) | SMN1; SMN2TSHRMAPTKMT2AMEN1 | |
| SCHEMBL6137225 | 0.82 | GLO1 (0.56) | SMN1; SMN2TSHRMAPTKMT2AMEN1 | |
| SCHEMBL14499484 | 0.81 | MEN1 (0.53) | SMN1; SMN2MAPTKMT2AMEN1LMNA | |
| SCHEMBL3610679 | 0.80 | ALDH1A1 (0.67) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL15082797 | 0.80 | ALDH1A1 (0.67) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL3610678 | 0.80 | ALDH1A1 (0.67) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL28754819 | 0.80 | CA12 (0.53) | SMN1; SMN2MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369762-B1 | Pesticides | ROUSSEL UCLAF (FR) | 1993-12-29 | — | — | EP | disclosed |
| US-5202356-A | Insecticides, miticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-13 | — | — | US | disclosed |
| EP-0369762-A1 | Pesticides | ROUSSEL-UCLAF (FR) | 1990-05-23 | — | — | EP | disclosed |