Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 11/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9520527 | 1.00 | DNM1 (0.45) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL8716562 | 1.00 | DNM1 (0.45) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL9516645 | 1.00 | DNM1 (0.45) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL9516625 | 1.00 | DNM1 (0.45) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL9518723 | 1.00 | DNM1 (0.45) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| SCHEMBL27284076 | 0.98 | DNM1 (0.45) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| SCHEMBL9076107 | 0.98 | DNM1 (0.45) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| SCHEMBL28048081 | 0.98 | DNM1 (0.45) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| SCHEMBL8711523 | 0.98 | DNM1 (0.45) | DNM1HTTKMT2AHSP90AA1RAD52 | |
| Water SCHEMBL9248184 | 0.96 | DNM1 (0.43) | DNM1HTTKMT2AHSP90AA1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396934-B1 | CAUSTIC-FREE SWEETENING OF SOUR HYDROCARBON STREAMS | UOP (US) | 1993-03-10 | — | — | EP | disclosed |
| EP-0396934-A1 | Caustic-free sweetening of sour hydrocarbon streams | UOP (US) | 1990-11-14 | — | — | EP | disclosed |
| US-4908122-A | Contacting hydrocarbon in the presence of an oxidizing agent with a catalytic composite to oxidize mercaptans to disulfides | UOP (US) | 1990-03-13 | — | — | US | disclosed |
| US-4124493-A | Catalytic oxidation of mercaptan in petroleum distillate including alkaline reagent and substituted ammonium halide | UOP INC. (US) | 1978-11-07 | — | — | US | disclosed |