SCHEMBL9515730

SCHEMBL9515730

C=C(C)CNC(=O)C=C(C)C=C[C@]1(F)CC1c1ccc(Cl)c(Cl)c1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
SLC6A2 P23975 5/20 0.33
SLC6A4 P31645 5/20 0.33
SLC6A3 Q01959 2/20 0.33
RXRA P19793 2/20 0.31
RARB P10826 1/20 0.31
RARG P13631 1/20 0.31
PYGL P06737 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9516900 0.91
SCHEMBL9515305 0.87 RXRA (0.32) RXRARARBRARG
SCHEMBL9430436 0.87 RXRA (0.32) RXRARARBRARG
SCHEMBL9429915 0.87 RXRA (0.32) RXRARARBRARG
SCHEMBL9430503 0.87 RXRA (0.32) RXRARARBRARG
SCHEMBL9515299 0.86 HPGD (0.40) MEN1NPC1RAB9AKMT2ASLC6A2
SCHEMBL9400348 0.83 NPSR1 (0.38) SLC6A2SLC6A4SLC6A3RXRARARB
SCHEMBL8967736 0.83 NPSR1 (0.38) SLC6A2SLC6A4SLC6A3RXRARARB
SCHEMBL8967697 0.82 RXRA (0.44) SLC6A2SLC6A4SLC6A3RXRARARB
SCHEMBL27364424 0.81 MMP1 (0.38) MEN1KMT2ASLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0369762-B1 Pesticides ROUSSEL UCLAF (FR) 1993-12-29 EP claimed
US-5202356-A Insecticides, miticides THE WELLCOME FOUNDATION LIMITED (GB) 1993-04-13 US claimed
EP-0369762-A1 Pesticides ROUSSEL-UCLAF (FR) 1990-05-23 EP claimed
EP-0369762-B1 Pesticides ROUSSEL UCLAF (FR) 1993-12-29 EP disclosed
US-5202356-A Insecticides, miticides THE WELLCOME FOUNDATION LIMITED (GB) 1993-04-13 US disclosed
EP-0369762-A1 Pesticides ROUSSEL-UCLAF (FR) 1990-05-23 EP disclosed