Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9430395 | 1.00 | HPGD (0.40) | HPGDNOS3NOS1NOS2NPC1 | |
| SCHEMBL9430143 | 1.00 | HPGD (0.40) | HPGDNOS3NOS1NOS2NPC1 | |
| SCHEMBL9430130 | 1.00 | HPGD (0.40) | HPGDNOS3NOS1NOS2NPC1 | |
| SCHEMBL9515309 | 1.00 | HPGD (0.40) | HPGDNOS3NOS1NOS2NPC1 | |
| SCHEMBL9597892 | 1.00 | HPGD (0.40) | HPGDNOS3NOS1NOS2NPC1 | |
| SCHEMBL9515299 | 0.87 | HPGD (0.40) | HPGDNOS3NOS1NOS2NPC1 | |
| SCHEMBL9430056 | 0.85 | NOS2 (0.38) | HPGDNOS3NOS1NOS2NPC1 | |
| SCHEMBL9597565 | 0.85 | NOS2 (0.38) | HPGDNOS3NOS1NOS2NPC1 | |
| SCHEMBL9196458 | 0.78 | MMP1 (0.37) | HPGDNPC1RAB9ALMNAPOLB | |
| SCHEMBL9516830 | 0.77 | EPHX2 (0.34) | HPGDLMNAKDM4EEPHX2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202356-A | Insecticides, miticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-13 | — | — | US | disclosed |
| EP-0369762-A1 | Pesticides | ROUSSEL-UCLAF (FR) | 1990-05-23 | — | — | EP | disclosed |