SCHEMBL9516833

SCHEMBL9516833

O=C1C=C(N(c2ccccc2)[N+](=O)[O-])C(=O)N1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.35
CRHBP P24387 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
CRHR2 Q13324 1/20 0.35
TLR9 Q9NR96 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GSK3B P49841 2/20 0.33
LMNA P02545 1/20 0.31
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2211488 0.75 POLB (0.41) ALDH1A1MEN1CRHBPKMT2AATM
SCHEMBL564828 0.74 ALDH1A1 (0.50) ALDH1A1MEN1CRHBPKMT2AATM
SCHEMBL10490987 0.74 ALDH1A1 (0.50) ALDH1A1MEN1CRHBPKMT2AATM
SCHEMBL11342834 0.73 CES1 (0.49) ALDH1A1MEN1KMT2ATLR9GSK3B
Fluoride SCHEMBL27617831 0.72 ALDH1A1 (0.48) ALDH1A1MEN1CRHBPKMT2AATM
SCHEMBL28228778 0.72 ALDH1A1 (0.48) ALDH1A1MEN1CRHBPKMT2AATM
Hydrochloric Acid SCHEMBL28757835 0.72 ALDH1A1 (0.48) ALDH1A1MEN1CRHBPKMT2AATM
SCHEMBL9491075 0.71 USP2 (0.34) ALDH1A1MEN1KMT2AGSK3B
SCHEMBL10472943 0.69 KDM4E (0.34) ALDH1A1MEN1KMT2AL3MBTL1GSK3B
SCHEMBL10419380 0.66 KMT2A (0.42) ALDH1A1MEN1CRHBPKMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0546113-A1 NONLINEAR OPTICAL MATERIALS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-16 EP disclosed