Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516926 | 1.00 | HDAC1 (0.52) | HDAC1HDAC6HDAC4HDAC3HDAC7 | |
| SCHEMBL17338690 | 0.76 | HDAC1 (0.79) | HDAC1HDAC6HDAC4HDAC3HDAC7 | |
| SCHEMBL17338691 | 0.76 | HDAC1 (0.79) | HDAC1HDAC6HDAC4HDAC3HDAC7 | |
| SCHEMBL9516871 | 0.75 | ALDH1A1 (0.45) | HDAC1HDAC6HDAC4HDAC3HDAC7 | |
| SCHEMBL9518116 | 0.74 | ALOX5 (0.46) | MAPTKDM4EMEN1ALDH1A1CYP3A4 | |
| SCHEMBL9518105 | 0.74 | ALOX5 (0.46) | MAPTKDM4EMEN1ALDH1A1CYP3A4 | |
| SCHEMBL9518032 | 0.73 | HDAC1 (0.46) | HDAC1HDAC6HDAC4HDAC3HDAC7 | |
| SCHEMBL9518039 | 0.73 | HDAC1 (0.46) | HDAC1HDAC6HDAC4HDAC3HDAC7 | |
| SCHEMBL9643200 | 0.70 | HDAC1 (0.46) | HDAC1HDAC6HDAC4HDAC3HDAC7 | |
| SCHEMBL9515533 | 0.70 | KMT2A (0.38) | HDAC4MAPTKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219436-B1 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI CHEM IND (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-4902700-A | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0219436-A2 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1987-04-22 | — | — | EP | disclosed |