Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.49 |
| ▸ | TUBB | P07437 | 2/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5132141 | 0.92 | ALDH1A1 (0.71) | ALDH1A1CYP19A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL2019108 | 0.90 | KDM4E (0.72) | ALDH1A1CYP19A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL1299605 | 0.90 | ALDH1A1 (0.69) | ALDH1A1CYP19A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL13181141 | 0.90 | ALDH1A1 (0.69) | ALDH1A1CYP19A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL8868058 | 0.88 | ALDH1A1 (0.67) | ALDH1A1CYP19A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL8868051 | 0.88 | ALDH1A1 (0.67) | ALDH1A1CYP19A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL273470 | 0.87 | ALDH1A1 (1.00) | ALDH1A1CYP19A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL30541678 | 0.87 | ALDH1A1 (1.00) | ALDH1A1CYP19A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL6077097 | 0.87 | ALDH1A1 (0.65) | ALDH1A1CYP19A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL19921255 | 0.85 | ALDH1A1 (0.62) | ALDH1A1CYP19A1CYP3A4TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424860-B1 | Wholly aromatic polyamides, process for their preparation and products therefrom | HOECHST AG (DE) | 1993-12-01 | — | — | EP | disclosed |
| US-5097015-A | Fibers, filaments, films and sheets | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | disclosed |
| EP-0424860-A2 | Wholly aromatic polyamides, process for their preparation and products therefrom | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-02 | — | — | EP | disclosed |