Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19921255 | 0.89 | ALDH1A1 (0.62) | ALDH1A1TSHRCYP3A4HSD17B10TDP1 | |
| SCHEMBL9516946 | 0.88 | ALDH1A1 (0.77) | ALDH1A1TSHRCYP3A4HSD17B10TDP1 | |
| SCHEMBL687841 | 0.85 | GAA (0.67) | ALDH1A1TSHRCYP3A4TAAR1CYP19A1 | |
| SCHEMBL5132141 | 0.85 | ALDH1A1 (0.71) | ALDH1A1TSHRCYP3A4HSD17B10TDP1 | |
| SCHEMBL31045431 | 0.85 | ALDH1A1 (0.71) | ALDH1A1TSHRCYP3A4HSD17B10TDP1 | |
| SCHEMBL4096678 | 0.85 | ALDH1A1 (0.71) | ALDH1A1TSHRCYP3A4HSD17B10TDP1 | |
| SCHEMBL13181141 | 0.83 | ALDH1A1 (0.69) | ALDH1A1TSHRCYP3A4HSD17B10TDP1 | |
| SCHEMBL2019108 | 0.83 | KDM4E (0.72) | ALDH1A1TSHRCYP3A4HSD17B10TDP1 | |
| SCHEMBL1299605 | 0.83 | ALDH1A1 (0.69) | ALDH1A1TSHRCYP3A4HSD17B10TDP1 | |
| SCHEMBL13098004 | 0.82 | ATM (0.66) | ALDH1A1CYP3A4CYP19A1KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11254696-B2 | Dianilinopyrimidine compound for inhibiting kinase activity | SHENZHEN TARGETRX, INC. (CN) | 2022-02-22 | — | — | US | disclosed |
| US-20210087213-A1 | DIANILINOPYRIMIDINE COMPOUND FOR INHIBITING KINASE ACTIVITY | SHENZHEN TARGETRX, INC. (CN) | 2021-03-25 | — | — | US | disclosed |
| WO-2021005165-A1 | TETRAHYDROISOQUINOLINE COMPOUNDS | ALLINKY BIOPHARMA (ES) | 2021-01-14 | — | — | WO | disclosed |
| EP-3763711-A1 | TETRAHYDROISOQUINOLINE COMPOUNDS | Allinky Biopharma (ES) | 2021-01-13 | — | — | EP | disclosed |
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087213-A1 | DIANILINOPYRIMIDINE COMPOUND FOR INHIBITING KINASE ACTIVITY | ALK, BRAF, MUSK | ALDH1A1 1205/4885TSHR 2814/4885CYP3A4 1557/4885 |
| US-11254696-B2 | Dianilinopyrimidine compound for inhibiting kinase activity | ALK, BRAF, MUSK | ALDH1A1 1334/4885TSHR 2710/4885CYP3A4 1802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.