Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516996 | 1.00 | CYP3A4 (0.36) | CYP3A4HTR2AHTR2CHTR2BRXFP1 | |
| SCHEMBL9516979 | 1.00 | CYP3A4 (0.36) | CYP3A4HTR2AHTR2CHTR2BRXFP1 | |
| SCHEMBL9198675 | 0.85 | HTR2A (0.51) | CYP3A4HTR2AHTR2CHTR2BLMNA | |
| SCHEMBL15715833 | 0.85 | HTR2A (0.51) | CYP3A4HTR2AHTR2CHTR2BLMNA | |
| SCHEMBL9198668 | 0.85 | HTR2A (0.51) | CYP3A4HTR2AHTR2CHTR2BLMNA | |
| SCHEMBL7975868 | 0.85 | HTR2A (0.51) | CYP3A4HTR2AHTR2CHTR2BLMNA | |
| SCHEMBL1982086 | 0.83 | MAPT (0.38) | HTR2AHTR2CHTR2BHTTLMNA | |
| SCHEMBL23953829 | 0.82 | KDM1A (0.38) | CYP3A4LMNATSHRMAPTALDH1A1 | |
| SCHEMBL18198465 | 0.82 | KDM1A (0.38) | CYP3A4LMNATSHRMAPTALDH1A1 | |
| SCHEMBL8330356 | 0.74 | SLC9A1 (0.44) | CYP3A4HTR2AHTR2CHTR2BHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369762-B1 | Pesticides | ROUSSEL UCLAF (FR) | 1993-12-29 | — | — | EP | disclosed |
| US-5202356-A | Insecticides, miticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-13 | — | — | US | disclosed |
| EP-0369762-A1 | Pesticides | ROUSSEL-UCLAF (FR) | 1990-05-23 | — | — | EP | disclosed |