Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 6/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519639 | 0.96 | P4HTM (0.47) | P4HTMGABRA5PTPN1HDAC6HDAC1 | |
| SCHEMBL9517019 | 0.90 | GABRA5 (0.40) | P4HTMGABRA5HDAC6HDAC1SCN9A | |
| SCHEMBL9517881 | 0.88 | GABRA5 (0.53) | P4HTMGABRA5PTPN1HDAC6HDAC1 | |
| SCHEMBL9517942 | 0.88 | P4HTM (0.47) | P4HTMGABRA5PTPN1HDAC6HDAC1 | |
| SCHEMBL9515803 | 0.86 | P4HTM (0.49) | P4HTMGABRA5HDAC6HDAC1CXCR2 | |
| SCHEMBL9515706 | 0.85 | P4HTM (0.43) | P4HTMGABRA5PTPN1HDAC6HDAC1 | |
| SCHEMBL9516194 | 0.85 | GABRA5 (0.38) | P4HTMGABRA5HDAC6SCN9ACASP3 | |
| SCHEMBL9517187 | 0.83 | NPC1 (0.40) | P4HTMGABRA5HDAC6HDAC1SCN9A | |
| SCHEMBL9517918 | 0.83 | GABRA5 (0.43) | P4HTMGABRA5PTPN1SCN9A | |
| SCHEMBL9517966 | 0.82 | P4HTM (0.45) | P4HTMGABRA5PTPN1HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |