Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 9/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517918 | 0.92 | GABRA5 (0.43) | GABRA5P4HTMSCN9ASCN5AHPGD | |
| SCHEMBL9516194 | 0.92 | GABRA5 (0.38) | GABRA5P4HTMSCN9ASCN5AHDAC6 | |
| SCHEMBL9517187 | 0.90 | NPC1 (0.40) | GABRA5P4HTMSCN9ASCN5AHDAC6 | |
| SCHEMBL9519639 | 0.90 | P4HTM (0.47) | GABRA5P4HTMSCN9AHDAC6HDAC1 | |
| SCHEMBL9517010 | 0.90 | P4HTM (0.47) | GABRA5P4HTMSCN9AHDAC6HDAC1 | |
| SCHEMBL9516209 | 0.90 | P4HTM (0.38) | GABRA5P4HTMSCN9ASCN5AHDAC6 | |
| SCHEMBL9516888 | 0.89 | GABRA5 (0.50) | GABRA5P4HTMSCN9AHDAC6HPGD | |
| SCHEMBL9516040 | 0.87 | GABRA5 (0.41) | GABRA5P4HTMHDAC6 | |
| SCHEMBL9516086 | 0.85 | GABRA5 (0.41) | GABRA5P4HTMSCN9ASCN5ANPC1 | |
| SCHEMBL9519237 | 0.85 | P4HTM (0.55) | P4HTMSCN9ASCN5AHDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |