Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472111 | 0.65 | ALDH1A1 (0.41) | MAPTALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL817452 | 0.65 | ALDH1A1 (0.41) | MAPTALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL2586974 | 0.65 | MAPT (0.46) | MAPTALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL12559863 | 0.65 | ALDH1A1 (0.41) | MAPTALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL11311453 | 0.65 | ALDH1A1 (0.41) | MAPTALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL817451 | 0.65 | ALDH1A1 (0.41) | MAPTALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL28404458 | 0.65 | ADAM17 (0.34) | ALDH1A1KDM4EMEN1GAAKMT2A | |
| SCHEMBL30676805 | 0.63 | — | — | |
| SCHEMBL28405609 | 0.63 | MEN1 (0.33) | ALDH1A1KDM4EMEN1GAAKMT2A | |
| SCHEMBL3646454 | 0.63 | ALDH1A1 (0.40) | MAPTALDH1A1HSD17B10KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216141-A | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR LINKAGES | BENNER, STEVEN | 1993-06-01 | — | — | US | disclosed |
| EP-0418309-A4 | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR | — | 1993-01-07 | — | — | EP | disclosed |
| EP-0418309-A1 | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR | BENNER, Steven Albert (CH) | 1991-03-27 | — | — | EP | disclosed |
| WO-1989012060-A1 | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR | BENNER STEVEN ALBERT (CH) | 1989-12-14 | — | — | WO | disclosed |