Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | BAX | Q07812 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517286 | 1.00 | KDM1A (0.49) | KDM1AMAOALTA4HTSHRKCNH2 | |
| SCHEMBL3970721 | 0.82 | KDM1A (0.57) | KDM1AMAOALTA4HTSHRKCNH2 | |
| SCHEMBL19322267 | 0.82 | KDM1A (0.57) | KDM1AMAOALTA4HTSHRKCNH2 | |
| SCHEMBL385172 | 0.82 | SLC18A3 (0.48) | — | |
| SCHEMBL8710331 | 0.79 | KDM1A (0.53) | KDM1ALTA4HTSHRNR1H2BAX | |
| SCHEMBL26154062 | 0.79 | KDM1A (0.53) | KDM1AMAOALTA4HTSHRKCNH2 | |
| SCHEMBL25187440 | 0.77 | DRD2 (0.47) | KDM1AMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7702531 | 0.77 | HAO1 (0.53) | KDM1ALTA4HTSHRKCNH2HRH3 | |
| SCHEMBL7698322 | 0.74 | KDM1A (0.58) | KDM1AMAOALTA4HTSHRKCNH2 | |
| SCHEMBL949252 | 0.74 | SLC18A3 (0.68) | KDM1ALTA4HSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559743-A1 | NOVEL HYDROXAMIC ACID AND N-HYDROXYUREA DERIVATIVES AND THEIR USE. | PFIZER HOSPITAL PROD (US) | 1993-09-15 | — | — | EP | disclosed |
| WO-1992009566-A1 | NOVEL HYDROXAMIC ACID AND N-HYDROXYUREA DERIVATIVES AND THEIR USE | PFIZER INC. (US) | 1992-06-11 | — | — | WO | disclosed |