Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3053407 | 0.95 | ALDH1A1 (0.36) | CRBNOR51E2LMNATSHRALDH1A1 | |
| SCHEMBL432189 | 0.93 | MAPT (0.35) | CRBNOR51E2LMNATSHRALDH1A1 | |
| SCHEMBL432190 | 0.93 | MAPT (0.35) | CRBNOR51E2LMNATSHRALDH1A1 | |
| SCHEMBL17338063 | 0.91 | ALDH1A1 (0.36) | CRBNOR51E2LMNATSHRALDH1A1 | |
| SCHEMBL6675762 | 0.91 | SRD5A1 (0.33) | LMNATSHRALDH1A1PKMSRD5A1 | |
| SCHEMBL9359669 | 0.91 | SRD5A1 (0.33) | LMNATSHRALDH1A1PKMSRD5A1 | |
| SCHEMBL6652266 | 0.89 | KMT2A (0.35) | CRBNOR51E2LMNATSHRALDH1A1 | |
| SCHEMBL12032976 | 0.87 | CRBN (0.32) | CRBNOR51E2 | |
| SCHEMBL3046579 | 0.86 | ALDH1A1 (0.36) | LMNATSHRALDH1A1PKMSRD5A1 | |
| SCHEMBL6638258 | 0.86 | ALDH1A1 (0.36) | LMNATSHRALDH1A1PKMSRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279350-B1 | Fused azepinone and azocinone derivatives , process for their preparation, agents containing them and their use, as well as their intermediates during their production | HOECHST AG (DE) | 1993-12-01 | — | — | EP | disclosed |
| US-4857520-A | Fused azepinone and azocinone derivatives, processes for their preparation, agents containing them and their use, and intermediates in their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-15 | — | — | US | disclosed |
| EP-0279350-A2 | Fused azepinone and azocinone derivatives , process for their preparation, agents containing them and their use, as well as their intermediates during their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-24 | — | — | EP | disclosed |