SCHEMBL6675762

SCHEMBL6675762

O=C1CCC2CCCC2N1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 1/20 0.33
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.31
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9359669 1.00 SRD5A1 (0.33) SRD5A1LMNATSHRALDH1A1PKM
SCHEMBL6638258 0.95 ALDH1A1 (0.36) SRD5A1LMNATSHRALDH1A1PKM
SCHEMBL8465326 0.95 ALDH1A1 (0.36) SRD5A1LMNATSHRALDH1A1PKM
SCHEMBL5567030 0.95 ALDH1A1 (0.36) SRD5A1LMNATSHRALDH1A1PKM
SCHEMBL3046579 0.95 ALDH1A1 (0.36) SRD5A1LMNATSHRALDH1A1PKM
SCHEMBL9733421 0.93 MAPT (0.35) SRD5A1LMNATSHRALDH1A1PKM
SCHEMBL9733418 0.93 MAPT (0.35) SRD5A1LMNATSHRALDH1A1PKM
SCHEMBL9517429 0.91 CRBN (0.35) SRD5A1LMNATSHRALDH1A1PKM
SCHEMBL26673240 0.88 SRD5A1 (0.38) SRD5A1LMNATSHRALDH1A1PKM
SCHEMBL18150856 0.86 SRD5A1 (0.37) SRD5A1LMNATSHRALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170114032-A1 SUBSTITUTED UREA DERIVATIVES AND PHARMACEUTICAL USES THEREOF SUNSHINE LAKE PHARMA CO., LTD. (CN) 2017-04-27 US disclosed
EP-0713702-B1 ANXIOLYTIC AGENT TAIHO PHARMACEUTICAL CO LTD (JP) 2004-09-29 EP disclosed
US-6500819-B2 HAS AN EXCELLENT ANXIOLYTIC EFFECT TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 2002-12-31 US disclosed
US-20020099048-A1 Bicycloloactam compounds, use thereof and intermediates for preparing thereof TAIHO PHARMACEUTICAL COMPANY LIMITED 2002-07-25 US disclosed
US-6355668-B1 ANXIOLYTIC AGENTS; SIDE EFFECT REDUCTION TAIHO PHARMACEUTICAL CO., LTD. (JP) 2002-03-12 US disclosed
US-6303623-B1 TREATING ANXIETY IN A PATIENT IN NEED OF SUCH TREATMENT, COMPRISING ADMINISTERING BICYCLOLACTAM COMPOUND TAIHO PHARMACEUTICAL CO LTD (JP) 2001-10-16 US disclosed
US-6159987-A Bicyclolactam compounds, use thereof and intermediates for preparing thereof TAIHO PHARMACEUTICALS, CO. (JP) 2000-12-12 US disclosed
US-6004975-A ANXIOLYTIC AGENTS WITH SIDE EFFECT REDUCTION TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1999-12-21 US disclosed
EP-0713702-A1 ANXIOLYTIC AGENT TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1996-05-29 EP disclosed
EP-0466933-B1 BICYCLOLACTAM DERIVATIVE TAIHO PHARMACEUTICAL CO LTD (JP) 1995-11-22 EP disclosed
EP-0668268-A2 Bicyclolactam derivatives for improving cerebral functions TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1995-08-23 EP disclosed
US-5214039-A Cognition activators TAIHO PHARMACEUTICAL CO., LIMITED (JP) 1993-05-25 US disclosed
US-5185344-A Improve cerebral function, activate cerebral metabolism, protect against anoxic brain damage TAIHO PHARMACEUTICAL COMPANY, LTD. (JP) 1993-02-09 US disclosed
EP-0466933-A1 BICYCLOLACTAM DERIVATIVE TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1992-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170114032-A1 SUBSTITUTED UREA DERIVATIVES AND PHARMACEUTICAL USES THEREOF ULK2, ULK3, ULK1 SRD5A1 3104/4885LMNA 2340/4885TSHR 3190/4885
US-20020099048-A1 Bicycloloactam compounds, use thereof and intermediates for preparing thereof CYP11B1, GABRA6, CYP11B2 SRD5A1 913/4885LMNA 436/4885TSHR 4141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.