Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 2/20 | 0.30 |
| ▸ | MMP9 | P14780 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517478 | 0.88 | — | — | |
| SCHEMBL9516487 | 0.88 | — | — | |
| Ethylenediamine SCHEMBL9516578 | 0.74 | MEN1 (0.41) | THRBMEN1KMT2A | |
| Dibromoacetic Acid SCHEMBL30556381 | 0.70 | THRB (0.46) | THRBMEN1KMT2AANPEPERAP2 | |
| Cadaverine Tartrate SCHEMBL30432913 | 0.70 | THRB (0.46) | THRBMEN1KMT2AANPEPERAP2 | |
| SCHEMBL9517544 | 0.69 | EPHX2 (0.33) | MMP2MMP9CA12CA1CA2 | |
| SCHEMBL9516723 | 0.69 | — | — | |
| SCHEMBL9514924 | 0.69 | EPHX2 (0.33) | MMP2MMP9CA12CA1CA2 | |
| SCHEMBL9516450 | 0.69 | EPHX2 (0.33) | MMP2MMP9CA12CA1CA2 | |
| SCHEMBL9517602 | 0.69 | EPHX2 (0.33) | MMP2MMP9CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341409-B1 | Platinum (II) complexes, their preparation and use as antitumour agents | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-12-29 | — | — | EP | disclosed |