Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3BCHECHRM1CHRM2CHRM3CHRM4CHRNA3CHRNA4CHRNB2CHRNB4ESR1ESR2GABRA1GABRB1GABRG2GBA1GHSRHRH1HTR1DHTR2AMAOBOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8UGCGrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dibromoacetic Acid SCHEMBL30556381 | 0.82 | THRB (0.46) | THRBMEN1KMT2AMMP2MMP9 | |
| Isocitric Acid SCHEMBL3179346 | 0.82 | CA4 (0.35) | THRBMEN1KMT2AMMP2MMP9 | |
| Isocitric Acid SCHEMBL2198195 | 0.82 | CA4 (0.35) | THRBMEN1KMT2AMMP2MMP9 | |
| Cadaverine Tartrate SCHEMBL30899742 | 0.81 | TSHR (0.50) | THRBMEN1KMT2AMMP2MMP9 | |
| Cadaverine Tartrate SCHEMBL918361 | 0.81 | TSHR (0.50) | THRBMEN1KMT2AMMP2MMP9 | |
| Tartaric Acid SCHEMBL30276688 | 0.81 | TSHR (0.50) | THRBMEN1KMT2AMMP2MMP9 | |
| Cadaverine Tartrate SCHEMBL30899743 | 0.81 | TSHR (0.50) | THRBMEN1KMT2AMMP2MMP9 | |
| Cadaverine Tartrate SCHEMBL1155812 | 0.81 | TSHR (0.50) | THRBMEN1KMT2AMMP2MMP9 | |
| Cadaverine Tartrate SCHEMBL17439178 | 0.81 | TSHR (0.50) | THRBMEN1KMT2AMMP2MMP9 | |
| Cadaverine Tartrate SCHEMBL5804440 | 0.81 | TSHR (0.50) | THRBMEN1KMT2AMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3845544-B1 | PHOSPHATE OF PLATINUM COMPOUND AND PREPARATION METHOD THEREFOR | BEIJING SHOWBY PHARMACEUTICAL CO LTD (CN) | 2023-11-15 | — | — | EP | disclosed |
| US-11661434-B2 | Phosphate of platinum compound and preparation method therefor | BEIJING SHOWBY PHARMACEUTICAL CO., LTD. (CN) | 2023-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11661434-B2 | Phosphate of platinum compound and preparation method therefor | BPGM, SLC16A1, MVD | THRB 3780/4885MEN1 148/4885KMT2A 2887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.